
Lung Transplant Surgery in India: A Complete Guide
For those suffering from end-stage lung diseases, a lung transplant is a life-saving surgery and can be a great source of relief. Lung transplant surgery is a complex and life-saving procedure that is used to treat certain types of lung diseases, such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, bronchiectasis and cystic fibrosis. Although still in its infancy, Lung transplant surgery in India has made tremendous progress in recent years, with many highly qualified and experienced doctors taking up this challenge. This guide will provide a comprehensive overview of the process of a lung transplant surgery in India, the different types of surgeries available, the success rates, and the cost involved. It will also address the risks and complications associated with the procedure. With this guide, you will have all the information you need to make an informed decision about whether a lung transplant is right for you and how to proceed with the procedure in India. Overview of Lung Transplant in India Lung transplantation is used to treat certain types of lung diseases, such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, bronchiectasis, cystic fibrosis, pulmonary arterial hypertension etc. These diseases can cause damage to the patient’s lungs, leading to shortness of breath, a decreased ability to exercise, and an increased risk of infection. In 1999, Dr. KM Cherian performed the first double-lung transplantation and the first combined heart–lung transplantation in India. This marked the beginning of the era of Lung transplantation in India. However the initial enthusiasm soon lost steam, until 2011 when another single lung transplant was done in Chennai. India has seen a tremendous growth in the numbers of lung transplants 2017 onwards with more and more centres taking up this challenge. A report published in Lancet Global Health suggests that the burden of chronic respiratory disease in India accounts for 32% of the global burden. Clearly these numbers indicate an unmet need for more trained transplant professionals and transplant centres across India. Thankfully many new transplant centres are coming up and India is slowly but surely coming of age as regards lung transplant. For people with advanced lung diseases termed as “End Stage Lung Disease”, lung transplantation may be the only option for a long-term cure. Lung transplant surgery is a life-saving procedure that can significantly improve quality of life for patients as well as their longevity. However, it is a complex procedure that carries certain risks. Therefore, it is essential to be fully informed about the procedure and its associated risks before making a decision about whether to proceed with Lung Transplant Surgery in India. For all general information related to lung transplant, you can watch this video in Hindi: Types of Lung Transplant Surgery There are broadly four types of transplant surgeries that may be used to treat end stage lung diseases: The type of Lung Transplant Surgery in India is determined by the extent of damage to the patient’s lungs, underlying etiology, availability of donor lungs and patient profile. Both single and double lung transplants have been performed for common indications including chronic obstructive pulmonary disease (COPD), interstitial lung disease (ILD), and primary pulmonary hypertension. Lung transplant operations, unlike other solid organ transplants, are somewhat unique in the fact that the donor block may be utilized for one recipient for a bilateral transplant or split to potentially benefit two patients with a single lung transplant each. Single-lung transplant: In this surgery, the diseased lung is removed and replaced with a healthy lung from another donor (cadaveric). The better out of the two lungs of the recipient is preserved. The donor lung is connected to the patient’s pulmonary veins and arteries to provide blood flow to the new lung and to the bronchus (airway). This surgery can be done on ECMO/heart-lung machine or off-pump. Double-lung transplant: This is the most common form of lung transplantation worldwide as well as in India. In this surgery a pair of donor lungs are required from a brain-dead donor. The diseased patient’s lungs are removed one after the other and the healthy donor lungs are sequentially connected to the patient’s pulmonary blood vessels and bronchus. Double Lung transplant is the only acceptable transplant modality in patients with septic lung disease like cystic fibrosis or bronchiectasis for obvious concerns about contaminating the new lung with preexisting infection. This surgery can also be done on ECMO/heart-lung machine or off-pump. Living Donor Lobar Lung Transplant: In living lobar lung transplantation, two healthy donors are selected—one to undergo removal of the right lower lobe and the other to undergo removal of the left lower lobe. These lobes are then implanted in the recipient in place of whole right and left lungs. Heart Lung Transplant: A heart-lung transplant is a major operation to replace a person’s diseased heart and lungs with those from a donor. It’s offered to people with both heart and lung failure when all other treatment options have failed. This surgery is done on a heart-lung bypass machine. The donated heart and lungs will be put en-bloc in place and connected to the surrounding blood vessels and the windpipe (trachea) Indications for Lung Transplant Surgery in India Most candidates for lung transplant surgery will have been diagnosed with an End Stage Lung Disease. These are the common diagnosis for which lung transplantation is done: Eligibility Criteria for Lung Transplant Patients need to meet a broad range of criteria to be eligible for Lung Transplant Surgery in India. They must: Pre-operative Preparation for Lung Transplant Surgery Preparation for lung transplant surgery includes both medical and psychological aspects. Medical: The medical team will assess your overall health to determine whether you are a good candidate for surgery. This is called “Lung Transplant Evaluation”. Based on the assessment you will be ‘listed’ for a lung transplant with the national and regional organ regulatory bodies (ROTTO, SOTTO, NOTTO) , if found fit. They will then monitor your progress while you are on the waiting list to see if you continue to meet the






